With the development of medical level, the update and iteration of clinical pathogenic bacteria and the emergence of super drug-resistant bacteria, severe infection has become a thorny problem faced by doctors. In order to promote the improvement of the level of diagnosis and treatment of infection, to understand a disease in the field of severe infection through the combination of theory and practice, to understand the clinical and imaging manifestations of the disease, as well as the mechanism and safety of therapeutic drugs through multidisciplinary MDT, and to bring diagnosis and treatment thoughts to clinicians through the sharing of difficult cases. On May 24, 2023, Chengdu High-tech Medical Association held the second session of the "Sixiang Storm" series exchange meeting online in Chengdu. The meeting invited well-known experts in the field of severe infection inside and outside the province to give a special academic report to discuss various types of anti-infection diagnosis and treatment around severe infection.