In order to promote the construction and development of skin immunity and rare diseases, and improve the clinical diagnosis and treatment level of dermatology inside and outside the region, the Chengdu High tech Medical Association held an online "New Developments in Skin Immunity and Rare Disease Diagnosis and Treatment Exchange Conference" on March 28 and March 30, 2025. This conference is hosted by the Chengdu High tech Medical Association and organized by the Skin Rare Disease Special Committee of the Dermatology and Beauty Credit Association of the Chengdu High tech Medical Association. Renowned experts in the field of dermatology were invited to give special academic presentations, focusing on classic cases and cutting-edge technologies related to skin immunology and rare diseases. We will share new concepts, progress, and information in the current clinical dermatology field with our colleagues, establish the concept of comprehensive and standardized treatment in dermatology, and expand international academic horizons. Representatives attending the conference expressed that they have benefited greatly.