Severe Infection Forum Successfully Held in Chengdu On September 18, 2025, the "Severe Infection Forum" sponsored by the Critical Care Medicine Professional Committee of Chengdu High-tech Medical Association and undertaken by Chengdu Hospital of Integrated Traditional Chinese and Western Medicine/Chengdu No.1 People's Hospital (hereinafter referred to as "Chengdu No.1 Hospital") was successfully held in the academic conference room on the 13th floor of Chengdu No.1 Hospital. The forum, themed "Rational Drug Use and Multidisciplinary Collaboration in Severe Infections", focused on clinical decision-making of antibacterial agents, review and management of special-class antibacterial agents, and prevention and control strategies for drug-resistant bacteria. Medical staff from departments including Critical Care Medicine, Respiratory and Critical Care Medicine, Pharmacy, Hematology, and Infection Control were invited to actively participate. ## Opening Speech: Facing Challenges and Clarifying Directions At the opening ceremony, Professor Xiong Ming, vice president of Chengdu No.1 Hospital, expressed gratitude to the experts attending the conference. She pointed out that the diagnosis and treatment of severe infections currently face multiple challenges, such as the increasing microbial drug resistance, the emergence of new pathogens, and the growing number of patients with complex underlying diseases. Rational use of antibacterial agents is a core link in infection prevention and control, requiring multidisciplinary collaboration. By standardizing diagnosis and treatment behaviors and optimizing management strategies, the level of infection treatment can be improved. --- ## Expert Leadership: Building an Integrated Medical-Nursing System for Drug-Resistant Bacteria Prevention and Control Professor Wang Bo from the Department of Critical Care Medicine, West China Hospital of Sichuan University, delivered the first report entitled "How Do I Implement Integrated Medical-Nursing Management for Multidrug-Resistant Organism Prevention and Control?". From the perspective of management practice, Professor Wang Bo elaborated on the organizational structure construction, process optimization plan, and multi-department collaboration mechanism for multidrug-resistant organism prevention and control. He emphasized the need to realize the systematization and standardization of drug-resistant bacteria prevention and control through the "medical-nursing-pharmacy-technical" integrated management model. --- ## Thematic Reports: Antibacterial Agent Selection in Clinical Practice The subsequent academic session focused on antibacterial agent application strategies in different clinical scenarios: - Professor Pan Ling'ai from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, gave a report entitled "How Do I Select Antibacterial Agents for Severe Infections in Hematology Patients?". She thoroughly discussed the pathogenic characteristics, drug selection principles, and treatment strategies for immunocompromised hosts with infections, providing practical guidance for anti-infection treatment in special populations. - Associate Chief Physician Wu Lingna from the Department of Critical Care Medicine, Chengdu No.1 Hospital, delivered a report entitled "How Do I Select Antibacterial Agents for Severe Pneumonia?". She systematically expounded on the etiological characteristics of severe pneumonia, the conversion strategy between empirical treatment and targeted treatment, and the key elements in formulating individualized treatment plans. - Professor Chen Jun from the Department of Critical Care Medicine, Jianyang People's Hospital, gave a report entitled "How Do I Implement De-escalation Anti-infection Treatment for Multidrug-Resistant Organism Infections?". He detailed the indication selection, timing grasp, plan formulation principles, and efficacy evaluation standards of de-escalation therapy, providing a complete path for the standardized clinical implementation of de-escalation therapy. - Professor Dong Qionglan from the Department of Critical Care Medicine, Mianyang No.3 People's Hospital, delivered a report entitled "How Do I Manage the Rational Application of Antibiotics?". From the perspective of department managers, she systematically introduced practical experience in the construction of clinical application management systems, process optimization, quality control, and performance assessment of antibacterial agents. - Associate Chief Physician Cao Lianghai from the Department of Critical Care Medicine, Chengdu No.1 Hospital, gave a report entitled "How Do I Review Special-Class Antibacterial Agents?". Combining specific cases, he elaborated on the indication grasp, review key points of medication plans, efficacy evaluation standards, and medication supervision skills for the use of special-class antibacterial agents. - Professor Yu Lan from the Pharmacy Department, Chengdu No.1 Hospital, delivered a report entitled "Treatment of Cryptococcal Meningitis - Selection and Monitoring of Amphotericin B Preparations". She in-depth analyzed the pharmacological characteristics, indication differences, dosage regimen formulation, and adverse reaction monitoring strategies of different amphotericin B preparations. - Attending Physician Dai Lei from the Department of Critical Care Medicine, Chengdu No.1 Hospital, shared a case of a patient with severe infection. Professor Zhang Yujing from the Infection Control Department of Chengdu No.1 Hospital, Professor Zhong Xingmei, Professor Zhu Yi, Attending Physician Luo Yunhao from the Department of Critical Care Medicine, Professor Zhang Kaiji, Director of the Hematology Department, Professor Wang Hui from the Department of Respiratory and Critical Care Medicine, Professor Yu Lan from the Pharmacy Department, and Attending Physician Huang Qiang from the Department of Critical Care Medicine, Wenjiang Hospital of Traditional Chinese Medicine, presided over the conference and participated in the discussions. Multidisciplinary experts conducted in-depth discussions on key issues such as etiological diagnosis ideas, antibacterial agent selection strategies, management points, and timing of treatment plan adjustments. There were both consensus reaching and viewpoints confrontation, with intense ideological collisions and a lively academic atmosphere on site. --- ## Cross-Border Integration: Emphasizing Both Management Innovation and Technological Innovation The forum demonstrated the hospital's management innovation and technological innovation practices in the field of severe infections. As a key provincial unit for the collaboration of traditional Chinese and Western medicine, the hospital actively explores the role of traditional Chinese medicine in infection prevention and control. Meanwhile, as a pilot unit for smart medical construction, it continuously promotes the application of artificial intelligence technology in infection etiological diagnosis, medication decision-making and other fields. --- ## Closing Summary: Standardizing Behaviors and Improving Quality The conference concluded successfully in a warm academic atmosphere. The prevention and control of severe infections need to adhere to the three principles of "rational drug use, multidisciplinary collaboration, and standardized management". By improving clinical diagnosis and treatment capabilities, optimizing management processes, and strengthening technological innovation, the dual goals of improving the quality of infection treatment and reducing drug resistance rates will ultimately be achieved. Focus on Infections, Rationalize Drug Use; Strengthen Multidisciplinary Collaboration, Jointly Build a Defense Line! We look forward to reuniting with you at the next academic feast to jointly promote the improvement of severe infection prevention and control capabilities!